CH Health Tech Advisory

Insights / Technology

Machine Learning

Field notes on Machine Learning in healthcare — the classical methods that still win, and where they hand off to newer techniques.

10 posts in Machine Learning

10 Mar 2026 · 4 min read

AI drug discovery benchmarks: why pharma needs model evaluation discipline

Three big AI drug discovery launches in 90 days: Boltz, IsoDDE, OpenFold3. Every benchmark was built by the team that built the model. The real question isn’t which model has the best benchmark. It’s whether discovery teams have a rigorous internal framework to evaluate any model that shows up. The real moat is evaluation discipline.

3 Mar 2026 · 2 min read

Lab-in-the-loop drug discovery is an operating model problem, not a model problem

Lab-in-the-loop gets talked about like it’s a model problem. The Roche/Novartis/Microsoft panel at health.tech | global summit Basel made the real point clearer: it’s an operating model problem. Most orgs are at Level 1–2 maturity, and that’s already useful — the first big value isn’t more hits, it’s faster, more confident kill decisions.

6 Oct 2025 · 1 min read

An exciting panel including Jan Schlender and Gunther Jansen, PhD of Novartis , Petrina Kamya, P...

I attended an exciting panel on GenAI's impact in preclinical development, featuring voices from Novartis, Insilico Medicine, and INVIDIA. Key themes included the balance of AI opportunity and risk, the power of robotics combined with AI, and the ongoing challenge of data organization and institutional memory in the lab.

15 Jul 2025 · 1 min read

Participating in this week's SNOMED International board meeting here at the historic Midland Manc...

Participating in the SNOMED International board meeting in Manchester reinforces my conviction that SNOMED CT is absolutely critical for healthcare AI. As a board member chairing the Technology and Innovation Committee, I see firsthand how this global standard transforms fragmented health data into a reliable, structured foundation for AI innovation.