CH Health Tech Advisory

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Strategic Planning

Posts carrying the Strategic Planning tag.

10 Mar 2026 · 4 min read

AI drug discovery benchmarks: why pharma needs model evaluation discipline

Three big AI drug discovery launches in 90 days: Boltz, IsoDDE, OpenFold3. Every benchmark was built by the team that built the model. The real question isn’t which model has the best benchmark. It’s whether discovery teams have a rigorous internal framework to evaluate any model that shows up. The real moat is evaluation discipline.

3 Mar 2026 · 2 min read

Lab-in-the-loop drug discovery is an operating model problem, not a model problem

Lab-in-the-loop gets talked about like it’s a model problem. The Roche/Novartis/Microsoft panel at health.tech | global summit Basel made the real point clearer: it’s an operating model problem. Most orgs are at Level 1–2 maturity, and that’s already useful — the first big value isn’t more hits, it’s faster, more confident kill decisions.

26 Feb 2026 · 3 min read

Clarivate LS&H sale: what GenAI means for pharma intelligence businesses

Clarivate is selling its LS&H division — $390M in revenue, down 7% YoY, stock at $1.69. Decision Resources and Cortellis defined pharma intelligence for decades. GenAI-native platforms are now structuring, querying, and synthesizing across the same data at a fraction of the cost. When organized access to information is your moat, and AI organizes information better than you, that’s not a strategy problem. That’s an existential one.

8 Oct 2025 · 3 min read

The AI-biology frontier: an inspiring panel this morning at BioTechX with Lena Afeyan of Flagsh...

I joined an inspiring panel this morning at BioTechX with investors from Flagship Pioneering, Hikma Pharmaceuticals, MTIP, Lauxera Capital Partners, and Archimed to discuss where we stand on the journey of cracking biology and health with AI. From agentic AI and defensible moats to the tech-bio platform vs. pipeline dilemma and whether we're in an AI bubble, the conversation covered the full frontier.

17 Jun 2025 · 1 min read

Some good learnings from the AIspotlight at HLTHEurope2025 on federated data and learning coll...

I share key learnings from the AIspotlight at HLTHEurope2025 on federated data and learning collaboration, where speakers from Roche, Charité, and beyond made the case for combining insights across institutions. A recurring theme: this shift in how we interact with health data requires clearer explanation and specific use cases for stakeholders.

10 Jun 2025 · 1 min read

I wrote last week about the two recent DigitalHealth IPOs. After the successful going public of...

I look at Omada Health's IPO following Hinge Health's successful public debut, noting that the valuation reflects a new market reality prioritizing a clear path to profitability over hyper-growth. I'm encouraged by the early performance but remain cautious about declaring the IPO window truly open again given ongoing macroeconomic uncertainty.

13 May 2025 · 1 min read

Last week at the AI in Clinical Development Summit 2025 in NYC, I had the pleasure of joining an...

Last week at the AI in Clinical Development Summit 2025 in NYC, I joined a panel tackling the timeless build-or-buy question for pharma AI in clinical development. Our consensus: a "build with" strategy — co-developing with selected strategic AI startup partners — strikes the right balance between speed, fit, and long-term value.

8 Apr 2025 · 1 min read

Traveling back from several intense days at the quarterly SNOMED International Management Board m...

I'm traveling back from several intense days at the quarterly SNOMED International Management Board meeting in Oslo, where I chair the Technology and Innovation Committee. Here's why internationally aligned clinical standards remain vital — and are even essential — for effective AI in healthcare.

6 Mar 2025 · 1 min read

A very insightful panel at the EPA lconference in Amsterdam from Gavin Lewis of Novartis, Annett...

I attended a very insightful panel at the EPA conference in Amsterdam on how global healthcare reforms are impacting local market access strategy. Modeling demands are becoming more challenging, joined Health Technology Assessments are increasingly the rule, and — as Gavin Lewis of Novartis put it — your access strategy is becoming your entire enterprise strategy.

29 Jan 2025 · 1 min read

A really insightful panel discussion on longevity at WHX Dubai (formerly Arab Health), hosted b...

I attended a really insightful panel discussion on longevity at WHX Dubai, and it challenged my assumption that longevity was mostly a US west coast buzzword. The UAE's patient safety-first, scientifically validated approach — combining genomics, AI, and precision medicine — could be a genuine game changer.

21 Jan 2025 · 1 min read

Wrapping up 3 productive days in Orlando, Florida and preparing to head back to Europe, following...

Wrapping up three productive days in Orlando following my first meeting as Chair of SNOMED International's Technology and Innovation Committee, I came away with one clear conviction: as we move into an era of AI-enabled healthcare systems, SNOMED CT as a common global language will be more crucial than ever for accurate, interoperable communication between humans and machines.

12 Dec 2024 · 1 min read

What if your AI assistant could truly understand not just your words, but your world? Meta's Chie...

I've written before about AI agents and their transformative potential to take action rather than just engage in conversation — and the industry is rapidly validating this vision. From Meta's Yann LeCun to Salesforce's Marc Benioff to Anthropic's Claude, the signals are clear: if you're not experimenting with AI agents today, you're falling behind.

10 Dec 2024 · 1 min read

A billion-dollar healthcare startup's dramatic fall, and a case-study for VC-founder tensions: Fo...

A lawsuit against VC firm Mohr Davidow Ventures over the collapse of billion-dollar healthcare startup HealthTap is a sobering case-study in the dark side of startup financing and the complex power dynamics between founders, employees, and investors. As an independent board member, I see these tensions regularly — and they'll only increase as 2021 valuations come back down to reality.

5 Sept 2024 · 1 min read

My AI agent will be in touch" — Could this be our near future?

I've been watching AI agents emerge as the next major frontier in GenAI, and the tipping point — when agents interact more with other agents than with humans — could be sooner than we think. From Amazon's aqui-hire of Adept to coding a working Pong game in under a minute with Claude 3.5, the shift from "brains in a jar" to machines that take real action is already underway.

6 Aug 2024 · 1 min read

A US judge has just ruled that Google is a "monopolist". I'm no lawyer, but I find it interesting...

A US judge has just ruled that Google is a "monopolist" — and I find it interesting that this judgment is arriving at a time when Google is probably challenged more than ever across its core business segments. It highlights both the importance of tech regulation and how slow the antitrust machinery moves compared to the speed of evolution in the tech sector.

25 Jul 2024 · 1 min read

It is fascinating to see, and pretty much a full time job in itself, to explore the continuous em...

I'm tracking the continuous emergence of new AI foundation models — from Mistral Large 2 to Meta's Llama 3.1 — as a billion-dollar arms race. My prediction: three types of models will emerge, and for healthcare, specialised imaging models like Microsoft's collaboration with Mass General Brigham are the ones to watch.

11 Jul 2024 · 1 min read

I've just shared here some days ago the somewhat encouraging stats around digital health investme...

I flagged some encouraging digital health investment stats recently, but a key leading indicator — how much VCs are raising for their funds — is not looking great, across all domains. Without a trend breaker in IPO and M&A exit opportunities, it will become even harder for healthtech companies to raise money in the future.

27 Jun 2024 · 1 min read

Despite the challenging fundraising environment, we are witnessing significant investments in AI-...

Despite the challenging fundraising environment, we are witnessing significant investments in AI-enabled drug discovery and development. Formation Bio's nearly $400M Series D and Xaira Therapeutics' emergence from stealth mode signal intensifying competition among major VC funds to lead in AI-powered biotech innovations.